Primary medical use
- For opioid-tolerant patients only: A single dose of 80mg is only for patients who are already tolerant to opioids of comparable potency.
- Risk of fatal overdose: Administering an 80mg dose to a patient who is not tolerant to opioids can cause fatal respiratory depression.
- Do not crush or chew: The tablets must be swallowed whole. Breaking, chewing, or crushing an OxyContin 80mg tablet will destroy its controlled-release mechanism, leading to a rapid and potentially fatal release of oxycodone.
- Not for as-needed use: The medication is intended to prevent pain around the clock, not to be taken on an as-needed basis









